B6db families : gaba-t

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gaba-t

Activity

Description

gamma-aminobutyrate--pyruvate aminotransferase (2.6.1.-)

Notes

The Arabidopsis enzyme uses preferentially pyruvate, rather than 2-oxoglutarate, as an amino group acceptor and is therefore distinct from EC 2.6.1.19. The sequences are similar to 2.6.1.18 (beta-alanine--pyruvate aminotransferase) and indeed this enzyme, too, is an omega-amino acid--pyruvate aminotransferase.

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Viridiplantae

AAQ14479 (Oryza sativa); AAO92257 (Lycopersicon esculentum); AAK52899.1 (Arabidopsis thaliana); AAO92255 (Lycopersicon esculentum); AAK11219.1 (Oryza sativa); AAO92256 (Lycopersicon esculentum); AAC78480.1 (Capsicum chinense);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

AAK52899.1

Domain interval

72-428

Catalytic site

327 K

References

Wu C, Zhou S, Zhang Q, Zhao W, Peng Y. (2006) Molecular cloning and differential expression of an gamma-aminobutyrate transaminase gene, OsGABA-T, in rice (Oryza sativa) leaves infected with blast fungus J Plant Res 119 663-9.

Palanivelu, R.; Brass, L.; Edlund, A.F.; Preuss, D. (2003) Pollen tube growth and guidance is regulated by POP2, an Arabidopsis gene that controls GABA levels Cell 114 933-41.47-59..

Van Cauwenberghe, O.R.; Makhmoudova, A.; McLean, M.D.; Clark, S.M.; Shelp, B.J. (2002) Plant pyruvate-dependent gamma-aminobutyrate transaminase:Identification of an Arabidopsis cDNA and its expression in Escherichia coli Can J Bot 80 933-41..

Articles on gaba-t

last changed

2008/09/01 11:35