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B6db families: l-lysine.2-aminotransferase.a

l-lysine 2-aminotransferase a
Activity l-lysine_2-aminotransferase
Description L-lysine 2-aminotransferase (2.6.1.-) (family a)
Notes Very small and homogeneous family, composed solely of sequences from Streptomycetes. The validated enzymes are involved in the biosynthesis of antibiotics such as virginiamycin S.

The family is phylogenetically very distinct from subfamily b and related instead to a number of NDP-hexose aminotransferases, such as 2.6.1.87 and perosamine aminotransferase (2.6.1.102).

PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 9
Sequences in seed alignment
BacteriaAF469950 (Streptomyces ansochromogenes); WP_005321557 (Streptomyces pristinaespiralis); ALE27497 (Streptomyces sp. NRRL 12068); WP_052287697 (Streptomyces sp. 769); AGN74881 (Streptomyces griseoviridis); WP_037348179 (Amycolatopsis sp. MJM2582); BAB83671 (Streptomyces virginiae); WP_033824881 (Kitasatospora sp. MBT63); CAA75797 (Streptomyces tendae);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence CAA75797
Domain interval 19-404
Catalytic site 193 K
 
References Articles on l-lysine.2-aminotransferase.a
last changed 2018/08/30 11:06

B6db families