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B6db families: mocr

Activity mocr
Description mocR-like proteins
Notes The family is composed of bacterial proteins that act primarily as transcriptional regulators, but retain an intact aminotransferase domain.
Indeed, all MocR-like regulators exhibit a PLP attachment site with a conserved lysine residue.

In C. glutamicum, genetic data suggest that a protein of the MocR family functions as an aminotransferase in valine biosynthesis. The gene encoding this protein is located upstream of a potential operon of a newly described pyridoxine biosynthetic pathway and when disrupted, gives rise to a pyridoxine auxotrophy.

PDB 5X03;
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 0
Reference sequence YCXD_BACSU
Domain interval 78-440
Catalytic site 286 K
References Articles on mocr
last changed 2017/10/26 14:42

B6db families