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B6db families: pumg

Activity pumg
Description Pseudouridine-5'-aldehyde aminotransferase (2.6.1.-)
Notes A family of enzymes based on the validated sequence from Streptomyces sp. ID38640.
They are most closely related to family lipo (which catalyzes a very similar reaction) and to other families FTI omega-aminotransferases such as (beta-alanine-pyruvate transaminase).
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 4
Sequences in seed alignment
BacteriaWP_031191256 (Streptomyces sp. NRRL B-11253); AVT42376 (Streptomyces sp. ID38640); ARZ66675 (Streptomyces albireticuli); WP_016471192 (Streptomyces albus DSM 40763);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence AVT42376
Domain interval 36-437
Catalytic site 289 K
 Sosio M, Gaspari E, Iorio M, Pessina S, Medema MH, Bernasconi A, Simone M, Maffioli SI, Ebright RH, Donadio S (2018) Analysis of the Pseudouridimycin Biosynthetic Pathway Provides Insights into the Formation of C-nucleoside Antibiotics Cell Chem Biol 25 540-549.

Articles on pumg
last changed 2018/04/04 17:11

B6db families