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B6db Fold_types: 3
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Fold type III

PLP-binding barrel. Circular permutation of the canonical fold: begins with an alpha helix and ends with a beta-strand.

Prototype sequence:
ALR_BACST - Alanine racemase

Prototype structure:
PDB 1sft;

Grishin Protein Sci. 1995

PLP-dependent families with this fold:

4.1.1.116 (0) 4.1.1.117 (0) 4.1.1.17_1 (0) 4.1.1.18_a (0) 4.1.1.18_d (0) 4.1.1.19_1 (0) 4.1.1.20 (0) 4.1.1.95 (0) 4.1.1.96 (0) 4.1.2.42 (0) 4.1.3.41 (0) 4.3.1.18_b (0) 4.3.1.27 (0) 5.1.1.12 (0) 5.1.1.1_a (0) 5.1.1.24 (0) 5.1.1.5_a (0) 5.1.1.5_b (0) 5.1.1.5_c (0) ctaf (0) d-aa deaminase (0) flvo (0) fslc (0) gm853 (0) mcce (0) odcp (0) smmdc (0) temporary_acse (0) uncharacterized_family_prosc (0) uncharacterized_family_yhfx (0) vino (0) xodc2 (0)
 Eswaramoorthy, S.; Gerchman, S,; Graziano, V.; Kycia, H.; Studier, F.W.; Swaminathan, S. (2003) Structure of a yeast hypothetical protein selected by a structural genomics approach. Acta Crystallogr D Biol Crystallogr. 59 127-135.

 Shaw, J.P.; Petsko, G.A.; Ringe, D. (1997) Determination of the structure of alanine racemase from Bacillus stearothermophilus at 1.9-A resolution. Biochemistry 36 1329-1342.


B6db Fold_types