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Home of B6-dependent enzymes

Enzymes that contain vitamin B6 – pyridoxal-5' phosphate (PLP) – as a cofactor are of great relevance to biology and medicine. B6-dependent enzymes belong to a small number of evolutionary lineages, but encompass more than 140 distinct catalytic functions, thus representing a remarkable example of divergent evolution.


You can access to the following information:
  • activity  Activities involving the B6 cofactor
  • seq  Sequences of B6-dependent enzymes
  • bib  References on B6-dependent activities and proteins
  • fam  Families of B6-dependent proteins
  • help  Help on the database usage

B6db statistics
  • Number of activities: 238
    • with EC number: 191
    • with known genes: 169
  • Numer of families: 205
  • Number of sequences: 2751
  • Number of references: 2271

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