2.6.1.82
Description	Putrescine aminotransferase
Alternative names	putrescine-α-ketoglutarate transaminase; YgjG; putrescine:α-ketoglutarate aminotransferase; PAT; putrescine:2-oxoglutarate aminotransferase; putrescine transaminase.
Catalyzed reaction	(1) putrescine + 2-oxoglutarate = 4-aminobutanal + L-glutamate (2) 4-aminobutanal = 1-pyrroline (spontaneous)
Cofactor	Pyridoxal-phosphate.
Comments	A pyridoxal-phosphate protein. The product, 4-aminobutanal, spontaneously cyclizes to form 1-pyrroline, which is a substrate for EC 1.5.1.35, 1-pyrroline dehydrogenase. Cadaverine and spermidine can also act as substrates. Forms part of the arginine-catabolism pathway.
	There is an overlap between this newly-classified activity and Diamine aminotransferase (2.6.1.29). The only function-verified gene (from E. coli) has been introduced into this database in the 2.6.1.29 family.
Organisms	-Eubacteria
Links	Enzyme (activities) 2.6.1.82 BRENDA (activities) 2.6.1.82 KEGG (pathways) 2.6.1.82 PLPMDB (PLP mutants) 2.6.1.82
References	Articles on 2.6.1.82
last changed	2010/02/02 10:28