B6db activities : 2_3_1

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2.3.1.47

Description

8-amino-7-oxononanoate synthase

Alternative names

AONS;
8-amino-7-ketopelargonate synthase;
7-keto-8-amino-pelargonic acid synthetase.;
7-KAP synthetase.
KAPA synthase;
alpha-Oxoamine Synthase (ambiguous;
BioF (gene name)

Catalyzed reaction

6-carboxyhexanoyl-CoA + L-alanine = 8-amino-7-oxononanoate + CoA + CO(2).

Cofactor

Pyridoxal-phosphate.

Comments

The known enzymes with this activity show a strict phylogenetic relationship to glycine acetyltransferases (EC 2.3.1.29).
Indeed, some of these enzymes possess a broad substrate specificity, performing also the glycine acetyltransferase reaction.

Prosite

PROSITE; PDOC00518;

PDB

1DJE; 1DJ9; 1BS0;

Organisms

-Eubacteria -Archea -Plants -Fungi

Family

2.3.1.47 (0)

Links

Enzyme (activities) 2.3.1.47
BRENDA (activities) 2.3.1.47
KEGG (pathways) 2.3.1.47
PLPMDB (PLP mutants) 2.3.1.47

References

B6db references :

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Articles on 2.3.1.47

last changed

2019/06/20 13:26