B6db activities : 2_6_1

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	2.6.1.111
Description	3-aminobutanoyl-CoA transaminase
Alternative names	acetoacetyl-CoA transaminase; kat (gene name); pucG (gene name);
Catalyzed reaction	3-aminobutanoyl-CoA + 2-oxoglutarate = acetoacetyl-CoA + L-glutamate
Cofactor	Pyridoxal phosphate.
Comments	-!- The enzyme, found in bacteria, is part of a L-lysine degradation pathway. -!- The enzyme is also active with other beta-amino compounds such as 3-amino-5-methylhexanoyl-CoA and 3-amino-3-phenylpropanoyl-CoA.
	-!- Characterization of an amminotransferate derived from a metagenome. This enzyme may be used in a variant route for lysine fermentation.
Organisms	-Eubacteria
Family	2.6.1.111 (0)

Links	Enzyme (activities) 2.6.1.111 BRENDA (activities) 2.6.1.111 KEGG (pathways) 2.6.1.111 PLPMDB (PLP mutants) 2.6.1.111

References	Perret A, Lechaplais C, Tricot S, Perchat N, Vergne C, Pellé C, Bastard K, Kreimeyer A, Vallenet D, Zaparucha A, Weissenbach J, Salanoubat M. (2011) A novel acyl-CoA beta-transaminase characterized from a metagenome PLoS One. 6 e22918. Articles on 2.6.1.111

last changed	2017/09/12 15:14

Family