B6db activities : 2_6_1

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	2.6.1.118
Description	[amino group carrier protein]-γ-(L-lysyl)-L-glutamate aminotransferase
Alternative names	[2-aminoadipate carrier protein]-aminoadipate semialdehyde/glutamate semialdehyde transaminase; LysJ.
Catalyzed reaction	an [amino group carrier protein]-C-terminal-γ-(L-lysyl)-L-glutamate + 2-oxoglutarate = an [amino group carrier protein]-C-terminal-N-(1-carboxy-5-oxopentan-1-yl)-L-glutamine + L-glutamate
Cofactor	Pyridoxal-phosphate.
Comments	The enzyme participates in an L-lysine biosynthesis pathway in certain species of archaea and bacteria.
	In Thermus aquaticus, the 2-aminoadipate carrier protein is termed LysW.
PDB	1VEF;
Organisms	-Eubacteria
Family	2.6.1.118 (0)

Links	Enzyme (activities) 2.6.1.118 BRENDA (activities) 2.6.1.118 KEGG (pathways) 2.6.1.118 PLPMDB (PLP mutants) 2.6.1.118

References	Horie A, Tomita T, Saiki A, Kono H, Taka H, Mineki R, Fujimura T, Nishiyama C, Kuzuyama T, Nishiyama M (2009) Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus Nat Chem Biol 5 673-9 . Articles on 2.6.1.118

last changed	2019/12/30 13:53

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