B6db activities : 2_6_1

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	2.6.1.22
Description	(S)-3-amino-2-methylpropionate aminotransferase
Alternative names	L-3-aminoisobutyrate aminotransferase.
Catalyzed reaction	(S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate
Cofactor	Pyridoxal-phosphate.
Comments	-!- Also acts on beta-alanine and other omega-amino acids having carbon chains between 2 and 5. -!- Not identical with EC 2.6.1.40.
	The activity has been described in metazoa. In rat liver, the enzyme seems to be identical to beta-alanine-oxo-glutarate aminotransferase (GABA transaminase; EC 2.6.1.19).
Organisms	-Metazoa

Links	Enzyme (activities) 2.6.1.22 BRENDA (activities) 2.6.1.22 KEGG (pathways) 2.6.1.22 PLPMDB (PLP mutants) 2.6.1.22

References	Tamaki, N.; Fujimoto, S.; Mizota, C.; Kikugawa, M. (1987) Identity of beta-alanine-oxo-glutarate aminotransferase and L-beta- aminoisobutyrate aminotransferase in rat liver Biochim Biophys Acta 925 238-40. Articles on 2.6.1.22

last changed	2009/05/19 14:53