B6db activities : 2_6_1

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	2.6.1.23
Description	4-hydroxyglutamate aminotransferase
Catalyzed reaction	4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate + L-glutamate
Cofactor	Pyridoxal-phosphate
Comments	Oxaloacetate can replace 2-oxoglutarate. May be identical with EC 2.6.1.1.
	The reaction catalyzed by this enzyme is part of the hydroxyproline degradation pathway, wich occurs in the mitochondria.
Organisms	-Metazoa

Links	Enzyme (activities) 2.6.1.23 BRENDA (activities) 2.6.1.23 KEGG (pathways) 2.6.1.23 PLPMDB (PLP mutants) 2.6.1.23

References	Maitra, U.; Dekker, E. (1964) Purification of rat liver gamma-hydroxyglutamate transaminase and its probable identity with glutamate-aspartate transaminase. Biochim Biophys Acta 81 517-32. Articles on 2.6.1.23

last changed	2009/04/30 12:06