B6db activities : 2_6_1

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	2.6.1.48
Description	5-aminovalerate aminotransferase
Alternative names	Delta-aminovalerate aminotransferase; Delta-aminovalerate transaminase; 5-aminopentanoate:2-oxoglutarate aminotransferase.
Catalyzed reaction	5-aminopentanoate + 2-oxoglutarate = 5-oxopentanoate + L-glutamate.
Cofactor	Pyridoxal-phosphate.
	The only tentatively identified genes (from Pseudomonas putida) are strictly related to bacterial GABA transaminases (EC 2.6.1.19) and have been included in family 2.6.1.19b.
Organisms	-Eubacteria -Fungi

Links	Enzyme (activities) 2.6.1.48 BRENDA (activities) 2.6.1.48 KEGG (pathways) 2.6.1.48 PLPMDB (PLP mutants) 2.6.1.48

References	Yamanishi Y, Mihara H, Osaki M, Muramatsu H, Esaki N, Sato T, Hizukuri Y, Goto S, Kanehisa M. (2007) Prediction of missing enzyme genes in a bacterial metabolic network. Reconstruction of the lysine-degradation pathway of Pseudomonas aeruginosa FEBS Lett 274 2262-73. Espinosa-Urgel, M., Ramos, J.L. (2001) Expression of a Pseudomonas putida aminotransferase involved in lysine catabolism is induced in the rhizosphere Appl Environ Microbiol 67 5219-24. Ichihara, A.; Ichihara, E.A.; Suda, M. (1960) Metabolism of L-lysine by bacterial enzymes. IV. d-Aminovaleric acid-glutamic acid transaminase. J. Biochem. (Tokyo) 48 412-20. Articles on 2.6.1.48

last changed	2019/01/08 10:05