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B6db activities: 2.6.1.51
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2.6.1.51
Description Serine--pyruvate aminotransferase
Alternative names alanine:glyoxylate aminotransferase 1;
serine:pyruvate/alanine:glyoxylate aminotransferase;
SPT;
SPIAT.
Catalyzed reaction L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.
Cofactor Pyridoxal-phosphate.
Comments -!- The liver enzyme may be identical with EC 2.6.1.44. include 2.6.1.44
Functionally validated enzymes with this activity in general also show alanine-glyoxylate aminotransferase activity (EC 2.6.1.44).
Their sequences are included in family 2.6.1.44_a.
Organisms -Eubacteria -Archea -Plants -Metazoa -Human
 
 
Links Enzyme (activities) 2.6.1.51
BRENDA (activities) 2.6.1.51
KEGG (pathways) 2.6.1.51
PLPMDB (PLP mutants) 2.6.1.51
 
References
 Noguchi, T.; Fujiwara, S. (1988) Identification of mammalian aminotransferases utilizing glyoxylate or pyruvate as amino acceptor. Peroxisomal and mitochondrial asparagine aminotransferase J Biol Chem 263 182-6.

Articles on 2.6.1.51
 
last changed 2019/08/19 10:25

B6db activities