B6db activities : 2_6_1

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	2.6.1.63
Description	Kynurenine--glyoxylate aminotransferase
Catalyzed reaction	L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine.
Cofactor	Pyridoxal-phosphate.
Comments	-!- Acts, more slowly, on L-phenylalanine, L-histidine and L-tyrosine.
	May be identical with aromatic amino acid-glyoxylate aminotransferase (EC 2.6.1.60). The enzyme from human liver is identical to serine-pyruvate/alanine-glyoxylate aminotransferase (EC 2.6.1.51).
Organisms	-Metazoa

Links	Enzyme (activities) 2.6.1.63 BRENDA (activities) 2.6.1.63 KEGG (pathways) 2.6.1.63 PLPMDB (PLP mutants) 2.6.1.63

References	Harada, I. (1980) Glucagon inducible kynurenine aminotransferase Wakayama Igaku (J Wakayama Med Soc) 31 61-68. Okuno, E.; Minatogawa, Y.; Nakamura, M.; Kamoda, N.; Nakanishi, J.; Makino, M.; Kido, R. (1980) Crystallization and characterization of human liver kynurenine-- glyoxylate aminotransferase. Identity with alanine--glyoxylate aminotransferase and serine--pyruvate aminotransferase Biochem J 189 581-90. Articles on 2.6.1.63

last changed	2019/05/21 12:30