B6db activities : 4_1_1

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	4.1.1.86
Description	Diaminobutyrate decarboxylase
Alternative names	DABA decarboxylase; L-2,4-diaminobutyrate decarboxylase.
Catalyzed reaction	L-2,4-diaminobutyrate = 1,3-diaminopropane + CO(2).
Cofactor	Pyridoxal-phosphate; divalent metal ion
Comments	-!- N(4)-acetyl-L-2,4-diaminobutanoate, 2,3-diaminopropanoate, ornithine and lysine are not substrates. -!-In Acinetobacter baumannii it is cotranscribed with the neighboring dat gene that encodes EC 2.6.1.76, which can supply the substrate for the decarboxylase.
PDB	2QMA;
Organisms	-Eubacteria
Family	4.1.1.86 (0)

Links	Enzyme (activities) 4.1.1.86 BRENDA (activities) 4.1.1.86 KEGG (pathways) 4.1.1.86 PLPMDB (PLP mutants) 4.1.1.86

References	Yamamoto, S.; Mutoh, N.; Tsuzuki, D.; Ikai, H.; Nakao, H.; Shinoda, S.; Narimatsu, S.; Miyoshi, S.I. (2000) Cloning and characterization of the ddc homolog encoding L-2,4-diaminobutyrate decarboxylase in Enterobacter aerogenes Biol Pharm Bull 23 649-53. Ikai, H.; Yamamoto, S. (1996) Sequence analysis of the gene encoding a novel L-2,4-diaminobutyrate decarboxylase of Acinetobacter baumannii: similarity to the group II amino acid decarboxylases Arch Microbiol 166 128-31. Articles on 4.1.1.86

last changed	2019/06/21 13:12

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