B6db activities : 4_3_1

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	4.3.1.20
Description	Erythro-3-hydroxyaspartate ammonia-lyase
Alternative names	3-hydroxyaspartate dehydratase (ambiguous).
Catalyzed reaction	Erythro-3-hydroxy-L-aspartate + H(2)O = oxaloacetate + NH(3) + H(2)O.
Cofactor	Pyridoxal-phosphate.
Comments	-!- The reaction catalyzed probably involves initial elimination of water (hence the enzyme's original classification as EC 4.2.1.38) followed by isomerization and hydrolysis of the product with C-N bond breakage. -!- Formerly EC 4.2.1.38.
Organisms	-Eubacteria -Metazoa

Links	Enzyme (activities) 4.3.1.20 BRENDA (activities) 4.3.1.20 KEGG (pathways) 4.3.1.20 PLPMDB (PLP mutants) 4.3.1.20

References	Gibbs RG, Morris JG. (1965) Purification and properties of erythro-beta-hydroxyasparate dehydratase from Micrococcus denitrificans Biochem J 97 547-54. Articles on 4.3.1.20

last changed	2019/06/20 13:03