B6db activities : 4_3_1

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	4.3.1.29
Description	D-glucosaminate-6-phosphate ammonia-lyase
Alternative names	DgaE; 6-phospho-D-glucosaminate ammonia-lyase (2-dehydro-3-deoxy-6-phospho-D-gluconate-forming)
Catalyzed reaction	2-amino-2-deoxy-D-gluconate 6-phosphate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + NH3
Cofactor	Pyridoxal-phosphate and Mn(II).
Comments	The enzyme, from the bacterium Salmonella typhimurium, is involved in the degradation pathway of 2-amino-2-deoxy-D-gluconate.
Organisms	-Eubacteria
Family	4.3.1.29 (0)

Links	Enzyme (activities) 4.3.1.29 BRENDA (activities) 4.3.1.29 KEGG (pathways) 4.3.1.29 PLPMDB (PLP mutants) 4.3.1.29

References	Phillips RS, Ting SC, Tetsadjio AG, Anderson KL, Friez KM, Miller KA, Hoover TR (2018) Properties and mechanism of d-glucosaminate-6-phosphate ammonia-lyase: An aminotransferase family enzyme with d-amino acid specificity Biochim Biophys Acta 1866 799-805. Miller KA, Phillips RS, Mrázek J, Hoover TR (2013) Salmonella utilizes D-glucosaminate via a mannose family phosphotransferase system permease and associated enzymes J Bacteriol 195 4057-66. Articles on 4.3.1.29

last changed	2018/02/12 17:50

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