B6db activities : 5_1_1

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	5.1.1.6
Description	Threonine racemase
Catalyzed reaction	L-threonine = D-threonine.
Cofactor	Pyridoxal-phosphate.
Comments	-!- Inverts both chiral centres.
	The described enzyme from Pseudomonas putida (included here because cited in BRENDA) is in fact a threonine-alpha-epimerase (inversion of stereochemistry on just the alpha carbon, with production of D-allo-Thr from L-Thr).
Organisms	-Eubacteria

Links	Enzyme (activities) 5.1.1.6 BRENDA (activities) 5.1.1.6 KEGG (pathways) 5.1.1.6 PLPMDB (PLP mutants) 5.1.1.6

References	Lim YH, Yokoigawa K, Esaki N, Soda K. (1993) A new amino acid racemase with threonine alpha-epimerase activity from Pseudomonas putida: purification and characterization J Bacteriol 175 4213-7. Amos, H. (1954) A racemase for threonine in Escherichia coli J Am Chem Soc 76 3858. Articles on 5.1.1.6

last changed	2017/12/22 09:55