B6db activities : cap15

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	cap15
Description	(5'S,6'R)-GlyU monooxygenase-decarboxylase (1.14.99.-)
Alternative names	Cap15 (gene name);
Catalyzed reaction	(5'S,6'R)-GlyU + O(2) = CarU(uridine-5'-carboxamide) + CO(2) + H(2)O
Cofactor	Pyridoxal phosphate
	Cap15 is involved in the biosynthesis of the antimycobacterial antibiotics capuramycins.
Organisms	-Eubacteria
Family	cap15 (0)

Links	Enzyme (activities) cap15 BRENDA (activities) cap15 KEGG (pathways) cap15 PLPMDB (PLP mutants) cap15

References	Huang Y, Liu X, Cui Z, Wiegmann D, Niro G, Ducho C, Song Y, Yang Z, Van Lanen SG. (2018) Pyridoxal-5'-phosphate as an oxygenase cofactor: Discovery of a carboxamide-forming, alfa-amino acid monooxygenase-decarboxylase. Proc Natl Acad Sci U S A. 115 974-979. Articles on cap15

last changed	2019/12/28 20:16

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