B6db activities : cndf

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	cndf
Description	1-piperideine 2-metyl 6-carboxylate syntase (2.5.1.-)
Alternative names	CndF (gene name);
Catalyzed reaction	(1) O-acetyl-L-homoserine + acetoacetate = 2-amino-6-oxo heptanoate + acetate (2) 2-amino-6-oxo heptanoate = 1-piperideine 2-metyl 6-carboxylate + H(2)O (spontaneous)
Cofactor	Pyridoxal-phosphate.
Comments	The enzyme (from Penicillum citrinum) participates in a pathway for the synthesis of the indole alkaloid citrinadin.
Organisms	-Fungi
Family	cndf (0)

Links	Enzyme (activities) cndf BRENDA (activities) cndf KEGG (pathways) cndf PLPMDB (PLP mutants) cndf

References	Chen M, Liu C-T, Tang Y (2020) Discovery and Biocatalytic Application of a PLP-Dependent Amino Acid γ-Substitution Enzyme that Catalyzes C-C Bond Formation J Am Chem Soc 142 10506-10515. Articles on cndf

last changed	2020/04/28 09:23

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