B6db activities : crmg

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	crmg
Description	4-hydroxy-2,2'-bipyridine-6-carbaldehyde aminotransferase (2.6.1.-)
Catalyzed reaction	4-hydroxy-2,2'-bipyridine-6-carbaldehyde + L-glutamate = 6-(aminomethyl)-2,2'-bipyridin-4-ol + 2-oxoglutarate
Cofactor	Pyridoxal phosphate
	The enzyme from Actinoalloteichus Sp. Wh1-2216-6 catalyzes a key transamination reaction in the biosynthesis of the potent immunosuppressnat Caerulomycin A.
PDB	5DDW;
Organisms	-Eubacteria
Family	crmg (0)

Links	Enzyme (activities) crmg BRENDA (activities) crmg KEGG (pathways) crmg PLPMDB (PLP mutants) crmg

References	Zhu Y, Xu J, Mei X, Feng Z, Zhang L, Zhang Q, Zhang G, Zhu W, Liu J, Zhang C. (2016) Biochemical and Structural Insights into the Aminotransferase CrmG in Caerulomycin Biosynthesis. ACS Chem Biol. 11 943-52. Articles on crmg

last changed	2018/03/07 13:47

Family