B6db activities : ind4

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	ind4
Description	Arginine 2,4-dioxidase (1.3.3.-)
Catalyzed reaction	L-Arginine + 2O(2) = 2,3,4,5 tetradehydroarginine + 2H(2)O(2)
Cofactor	Pyridoxal phosphate
Comments	??? The enzyme in vitro catalyzes other reactions involving miolecular oxygen, including the oxidative deamination of L-Arg.
	The enzyme, from Streptomyces griseus, is involved in indolmycin biosynthesis.
Organisms	-Eubacteria
Family	ind4 (0)

Links	Enzyme (activities) ind4 BRENDA (activities) ind4 KEGG (pathways) ind4 PLPMDB (PLP mutants) ind4

References	Du YL, Singh R, Alkhalaf LM, Kuatsjah E, He HY, Eltis LD, Ryan KS (2016) A pyridoxal phosphate-dependent enzyme that oxidizes an unactivated carbon-carbon bond Nat Chem Biol 12 194-9. Du YL, Alkhalaf LM, Ryan KS (2015) In vitro reconstitution of indolmycin biosynthesis reveals the molecular basis of oxazolinone assembly Proc Natl Acad Sci U S A 112 2717-22. Articles on ind4

last changed	2019/06/20 13:08

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