B6db activities : kans2

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	kans2
Description	Kanamicin aminotransferase (2.6.1.-)
Alternative names	KanS2 (gene name);
Catalyzed reaction	3"oxo-kanamicin A + L-glutamate => kanamicin A + 2-oxoglutarate.
Cofactor	Pyridoxal phosphate
Comments	The enzyme is involved in the biosynthesis of Kanamicins. In the opposite reaction, kanamicin B and C can functions as substrates as well
Organisms	-Eubacteria
Family	kans2 (0)

Links	Enzyme (activities) kans2 BRENDA (activities) kans2 KEGG (pathways) kans2 PLPMDB (PLP mutants) kans2

References	Kudo F, Kitayama Y, Miyanaga A, Hirayama A, Eguchi T (2020) Biochemical and Structural Analysis of a Dehydrogenase, KanD2, and an Aminotransferase, KanS2, That Are Responsible for the Construction of the Kanosamine Moiety in Kanamycin Biosynthesis Biochemistry 59 1470-1473. Articles on kans2

last changed	2020/04/28 07:53

Family