B6db activities : mm260

	Activities \| Families \| Sequences \| Fold types \| References \| Help


	mm260
Description	L-threonine kinase (decarboxylating) (2.7.1.-)
Catalyzed reaction	ATP + L-threonine = ADP + (R)-1-aminopropan-2-ol phosphate + CO(2).
Cofactor	Pyridoxal-phosphate.
	The enzyme from Methanosarcina is involved in the biosynthesis of cobamides and is the first example of a new class of l-Thr-P decarboxylases that also have l-Thr kinase activity.
Organisms	-Archea
Family	mm260 (0)

Links	Enzyme (activities) mm260 BRENDA (activities) mm260 KEGG (pathways) mm260 PLPMDB (PLP mutants) mm260

References	Tavares NK, Zayas CL, Escalante-Semerena JC (2018) The Methanosarcina mazei MM2060 Gene Encodes a Bifunctional Kinase/Decarboxylase Enzyme Involved in Cobamide Biosynthesis Biochemistry 57 4478-4495. Articles on mm260

last changed	2019/06/20 13:28

Family