B6db activities : sibq

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	sibq
Description	3-hydroxy-4-methylkynurenine hydrolase (3.7.1-)
Catalyzed reaction	3-Hydroxy-4-methyl-kynurenine + H(2)O = 3-hydroxy-4-methyl-anthranilate + Alanine.
Cofactor	Pyridoxal phosphate
	The enzyme sibq is involved in the biosynthesis of the antitumor antibiotic sibiromycin.
Organisms	-Eubacteria
Family	sibq (0)

Links	Enzyme (activities) sibq BRENDA (activities) sibq KEGG (pathways) sibq PLPMDB (PLP mutants) sibq

References	Giessen TW, Kraas FI, Marahiel MA. (2011) A four-enzyme pathway for 3,5-dihydroxy-4-methylanthranilic acid formation and incorporation into the antitumor antibiotic sibiromycin. Biochemistry 50 5680-92. Articles on sibq

last changed	2018/04/16 16:46

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