type	Journal Article
authors	Kido, R.; Noguchi, T.
title	Kynurenine pyruvate transaminase and its specific inhibitor in rat intestine
journal	Acta Vitaminol Enzymol
Activity	2.6.1.7
ui	78100145
year	(1975)
volume	29
number	1-6
pages	310-2
keywords	Animal
abstract	Kynurenine pyruvate transaminase was partially purified and characterized. The enzyme catalysed the conversion of L-knurenine to kynurenic acid. Transamination rates of 3-hydroxy-DL-kynurenine and 5- hydroxy-DL-kynurenine by the enzyme were 1/2.9 and 1/2.6 of kynurenine. The enzyme showed a higher preference for pyruvate than 2-oxoglutarate as aminoacceptor. The pH optimum of the reaction was 8.0 and 8.5. It was shown that the inhibitor of kynurenine pyruvate transaminase was present in the intestine.
last changed	2002/11/12 16:17