type	Journal Article
authors	Ikeda, M.; Okada, M.
title	Effect of pyridoxine deficiency on ornithine aminotransferase in rat kidney and liver
journal	J Nutr Sci Vitaminol (Tokyo)
Activity	2.6.1.13
ui	86199000
year	(1985)
volume	31
number	6
pages	553-61.
keywords	Animal
abstract	The hepatic and renal activities of ornithine aminotransferase (OAT) [L- ornithine 2-oxoacid aminotransferase, EC 2.6.1.13] were determined in male and female rats given diet with or without pyridoxine. OAT activities were measured in the presence of pyridoxal phosphate. Diet without pyridoxine caused a decrease in hepatic OAT activity in males and no change in females and an increase in renal OAT activity in males and a decrease in females. The increased renal OAT activity in males was associated with increased immunochemically recognizable OAT, and was due to increased synthesis of OAT as shown by measurement of [3H]leucine incorporation in vivo. Thus OAT is regulated by nutritional conditions in different ways in liver and kidney.
last changed	2002/11/04 17:41