type	Journal Article
authors	Schmidt, H.; Bode, R.; Birnbaum, D.
title	A novel enzyme, L-lysine : pyruvate aminotransferase, catalyses the first step of lysine catabolism in Pichia guilliermondii
journal	FEMS Microbiol. Lett.
Activity	2.6.1.71
sel	selected
ui	nelpacf
year	(1988)
volume	49
pages	203-206
abstract	Abstract A novel aminotransferase catalysing the first step of lysine catabolism, the oxidative transamination of the ϵ-group of L-lysine, was found and characterised in the yeast Pichia guilliermondii. The enzyme, L-lysine : pyruvate aminotransferase (Lys-AT), is strongly derepressed in cells grown on L-lysine as sole nitrogen source and its activity is highly specific for both L-lysine and pyruvate. We could successfully isolate a regulatory mutant which is unable to use lysine as sole nitrogen source based on its inability to derepress the Lys-AT.
last changed	2009/05/19 15:45