type	Journal Article
authors	Galman,J.L., Slabu,I., Weise,N.J., Iglesias,C., Parmeggiani,F., Lloyd,R.C. and Turner,N.J.
title	Biocatalytic transamination with near-stoichiometric inexpensive amine donors mediated by bifunctional mono- and di-amine transaminases
journal	Green Chem
Activity	2.6.1.113
Family	2.6.1.113
sel	selected
ui	NOT-in-medline
year	(2017)
volume	19
pages	361-366
keywords	benzylamines; biocatalysis; green chemistry; protein structure; transaminase
abstract	The discovery and characterisation of enzymes with both monoamine and diamine transaminase activity is reported, allowing conversion of a wide range of target ketone substrates with just a small excess of amine donor. The diamine co-substrates (putrescine, cadaverine or spermidine) are bio-derived and the enzyme system results in very little waste, making it a greener strategy for the production of valuable amine fine chemicals and pharmaceuticals.
last changed	2019/01/14 13:38