B6db families : 2_3_1_50

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2.3.1.50 c

Activity

2.3.1.50

Description

Serine C-palmitoyltransferase (family c)

Notes

A group of enzymes mostly from soil bacteria.

PDB

2JG2;3A2B ;2X8U;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

YP_001264383 (Sphingomonas wittichii RW1); EDM38415 (Pedobacter sp. BAL39); ZP_00094502 (Novosphingobium aromaticivorans); ZP_01126180 (Nitrococcus mobilis); BAF73752 (Sphingobacterium spiritivorum); ACI98179 (Rhodospirillum centenum SW); BAF73751 (Sphingobacterium multivorum); ZP_01863728 (Erythrobacter sp. SD-21); BAF73753 (Bacteriovorax stolpii); ZP_00090424 (Azotobacter vinelandii); CAD85566 (Nitrosomonas europaea ATCC 19718); AAV89894 (Zymomonas mobilis); NP_755586 (Escherichia coli CFT073); YP_631930 (Myxococcus xanthus DK 1622); BAB56013 (Sphingomonas paucimobilis); F87393 (Caulobacter crescentus); ZP_01308477 (Oceanobacter sp. RED65); YP_902424 (Pelobacter propionicus);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

BAB56013

Domain interval

65-409

Catalytic site

265 K

References

Ikushiro H, Islam MM, Tojo H, Hayashi H. (2007) Molecular characterization of membrane-associated soluble serine palmitoyltransferases from Sphingobacterium multivorum and Bdellovibrio stolpii J Bacteriol 189 5749-61.

Yard BA, Carter LG, Johnson KA, Overton IM, Dorward M, Liu H, McMahon SA, Oke M, Puech D, Barton GJ, Naismith JH, Campopiano DJ (2007) The structure of serine palmitoyltransferase; gateway to sphingolipid biosynthesis J Mol Biol 370 870-86.

Ikushiro, H, Hayashi, H, Kagamiyama, H. (2001) A water-soluble homodimeric serine palmitoyltransferase from Sphingomonas paucimobilis EY2395T strain. Purification, characterization, cloning, and overproduction J. Biol. Chem. 276 18249-18256.

Articles on 2.3.1.50.c

last changed

2014/03/05 11:18