B6db families : 2_5_1_48

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2.5.1.48 a

Activity

2.5.1.48

Description

Cystathionine gamma-synthase (family a)

Notes

Subfamily 2.5.1.48a includes a group of enzymes with cystathionine gamma-synthase activity that are found in gram-negative bacteria; subfamily b encompasses enzymes from plants (plastidial proteins) and cyanobacteria.

PDB

1CS1;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

METB_ECOLI (Escherichia coli); ZP_00039741 (Xylella fastidiosa Dixon); NP_760287 (Vibrio vulnificus CMCP6); NP_931916 (Photorhabdus luminescens subsp. laumondii TTO1); AAM42128 (Xanthomonas campestris); NP_719586 (Shewanella oneidensis MR-1); CAD83273 (Candidatus Blochmannia floridanus); NP_462981 (Salmonella typhimurium LT2);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

METB_ECOLI

Domain interval

6-381

Catalytic site

198 K

References

Wahl, M. C.; Huber, R.; Prade, L.; Marinkovic, S.; Messerschmidt, A.; Clausen, T. (1997) Cloning, purification, crystallization, and preliminary X-ray diffraction analysis of cystathionine gamma-synthase from E. coli FEBS Lett 414 492-6.

Articles on 2.5.1.48.a

last changed

2007/10/19 19:02