B6db families : 2_5_1_48

	Activities \| Families \| Sequences \| Fold types \| References \| Help

2.5.1.48 c

Activity

2.5.1.48

Description

Cystathionine gamma-synthase (family c)

Notes

This subfamily, based on the sequence WP_052846353 from S. tokadaii, includes a group of enzymes with cystathionine gamma-synthase activity from archaea.

Proteins very similar to those in family 4.4.1.11_a (Methionine gamma-lyase).

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

ARM75149 (Acidianus manzaensis); WP_054845462 (Sulfolobus sp. JCM 16833); EHP70685 (Metallosphaera yellowstonensis MK1); WP_048098899 (Candidatus Acidianus copahuensis); WP_012020635 (Metallosphaera sedula); WP_048052386 (Sulfolobus islandicus); EWG07846 (Sulfolobales archaeon AZ1); WP_013737992 (Metallosphaera cuprina); WP_011277835 (Sulfolobus acidocaldarius); WP_052846353 (Sulfolobus tokodaii);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

WP_052846353

Domain interval

4-371

Catalytic site

189 K

References

Sato D, Shiba T, Mizuno S, Kawamura A, Hanada S, Yamada T, Shinozaki M, Yanagitani M, Tamura T, Inagaki K, Harada S (2017) The hyperthermophilic cystathionine γ-synthase from the aerobic crenarchaeon Sulfolobus tokodaii: expression, purification, crystallization and structural insights Acta Crystallogr F Struct Biol Commun 73 152-158. .

Articles on 2.5.1.48.c

last changed

2018/03/05 13:25