B6db families : 2_6_1

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2.6.1.102

Activity

2.6.1.102

Description

GDP-perosamine synthase

Notes

A family of bacterial enzymes acting on NTP-aminohexoses and related to enzymes with similar activities, such as those in family 2.6.1.106.

PDB

1O69;3BN1;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

NP_419828 (Caulobacter crescentus CB15); YP_001114461 (Desulfotomaculum reducens); NP_229901 (Vibrio cholerae); BAA77728 (Escherichia coli); AAC98613 (Brucella melitensis); YP_003012242 (Paenibacillus sp. JDR-2); ZP_01093805 (Blastopirellula marina DSM 3645);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

NP_229901

Domain interval

7-361

Catalytic site

181 K

References

Cook PD, Holden HM. (2008) GDP-perosamine synthase: structural analysis and production of a novel trideoxysugar Biochemistry 47 2833-40.

Zhao G, Liu J, Liu X, Chen M, Zhang H, Wang PG. (2007) Cloning and characterization of GDP-perosamine synthetase (Per) from Escherichia coli O157:H7 and synthesis of GDP-perosamine in vitro Biochem Biophys Res Commun 363 525-30.

Albermann, C.; Piepersberg, W. (2001) Expression and identification of the RfbE protein from Vibrio cholerae O1 and its use for the enzymatic synthesis of GDP-D-perosamine Glycobiology 11 655-61.

Articles on 2.6.1.102

last changed

2017/09/08 09:22