B6db families : 2_6_1

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2.6.1.106

Activity

2.6.1.106

Description

dTDP-3-amino-3,4,6-trideoxy-α-D-glucose transaminase

Notes

Only one functionally validated gene product (from S. venezuelae).

The enzyme is phylogenetically related to 2.6.1.89 and to a number of other NDP-hexose aminotransferases.

PDB

2OGE;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

BAC57033 (Micromonospora griseorubida); AAC68680 (Streptomyces venezuelae); AAM88356 (Streptomyces narbonensis); WP_024756757 (Streptomyces exfoliatus DSMZ);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

AAC68680

Domain interval

20-370

Catalytic site

193 K

References

Burgie ES, Thoden JB, Holden HM. (2007) Molecular architecture of DesV from Streptomyces venezuelae: a PLP-dependent transaminase involved in the biosynthesis of the unusual sugar desosamine Protein Sci 16 887-96.

Articles on 2.6.1.106

last changed

2014/08/19 13:41