B6db families : 2_6_1

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2.6.1.109

Activity

2.6.1.109

Description

8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase

Notes

Family built on the functionally validated sequence from Shewanella.

PDB

5K8B;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

YP_006760124 (Desulfobacula toluolica Tol2); YP_004789757 (Muricauda ruestringensis DSM 13258); ETR70531 (Candidatus Magnetoglobus multicellularis str. Araruama); WP_006423196 (delta proteobacterium NaphS2); WP_020253972 (Cloacimonetes bacterium SCGC AAA255-B16); EWH12379 (Cellulophaga geojensis KL-A); WP_006965855 (Desulfotignum phosphitoxidans); WP_019557504 (Thiomicrospira arctica); YP_001531083 (Desulfococcus oleovorans Hxd3); NP_718063 (Shewanella oneidensis MR-1);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

NP_718063

Domain interval

6-390

Catalytic site

186 K

References

Zachman-Brockmeyer TR, Thoden JB, Holden HM (2016) Structures of KdnB and KdnA from Shewanella oneidensis: Key Enzymes in the Formation of 8-Amino-3,8-Dideoxy-d-Manno-Octulosonic Acid Biochemistry 55 4485-94.

Gattis SG, Chung HS, Trent MS, Raetz CR (2013) The origin of 8-amino-3,8-dideoxy-D-manno-octulosonic acid (Kdo8N) in the lipopolysaccharide of Shewanella oneidensis. J Biol Chem. 288 9216-25.

Articles on 2.6.1.109

last changed

2017/09/06 11:32