B6db families : 2_6_1

	Activities \| Families \| Sequences \| Fold types \| References \| Help

2.6.1.110

Activity

2.6.1.110

Description

dTDP-4-dehydro-2,3,6-trideoxy-D-glucose 4-aminotransferase

Notes

A small family based on the validated enzyme from Saccharopolyspora spinosa.

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

AAY88935 (Saccharopolyspora pogona); KPL32272 (Streptomyces anulatus); WP_077004288 (Saccharothrix sp. ALI-22-I); AAG23279 (Saccharopolyspora spinosa); ADM72812 (Kitasatospora aureofaciens); WP_027659900 (Salinispora pacifica); CAM96587 (Streptomyces ambofaciens);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

AAG23279

Domain interval

7-370

Catalytic site

182 K

References

Hong L, Zhao Z, Melançon CE 3rd, Zhang H, Liu HW (2008) In vitro characterization of the enzymes involved in TDP-D-forosamine biosynthesis in the spinosyn pathway of Saccharopolyspora spinosa J Am Chem Soc 130 4954-67.

Zhao Z, Hong L, Liu HW. (2005) Characterization of protein encoded by spnR from the spinosyn gene cluster of Saccharopolyspora spinosa: mechanistic implications for forosamine biosynthesis J Am Chem Soc 127 7692-3.

Articles on 2.6.1.110

last changed

2017/09/07 11:00