B6db families : 2_6_1_44

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2.6.1.44 b

Activity

2.6.1.44

Description

Alanine--glyoxylate aminotransferase (family b)

Notes

The validated enzyme (from T. litoralis) used to build this family is an archaeal protein not closely related to the eukariotic enzymes with alanine-glyoxylate aminotransferase activity.

PDB

2ZC0;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Archaea

YP_004176177 (Desulfurococcus mucosus DSM 2162); BAB40321 (Thermococcus litoralis); YP_002428362 (Desulfurococcus kamchatkensis 1221n); YP_005842545 (Fervidicoccus fontis Kam940); AHF80561 (Thermococcus sp. ES1); YP_006402307 (Desulfurococcus fermentans DSM 16532); YP_002307331 (Thermococcus onnurineus NA1); YP_004071325 (Thermococcus barophilus MP);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

BAB40321

Domain interval

34-397

Catalytic site

247 K

References

Sakuraba H, Yoneda K, Takeuchi K, Tsuge H, Katunuma N, Ohshima T. (2008) Structure of an archaeal alanine:glyoxylate aminotransferase Acta Crystallogr D Biol Crystallogr 64 696-9.

Sakuraba, H.; Kawakami, R.; Takahashi, H.; Ohshima, T. (2004) Novel archaeal alanine:glyoxylate aminotransferase from Thermococcus litoralis J Bacteriol 186 15292154.

Articles on 2.6.1.44.b

last changed

2009/03/11 13:08