B6db families : 2_6_1

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2.6.1.72

Activity

2.6.1.72

Description

D-4-hydroxyphenylglycine aminotransferase

Notes

The family has been constructed around the validated sequence with this activity, from Pseudomonas stutzeri.

PDB

2CY8;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

ZP_01852170 (Planctomyces maris DSM 8797); WP_051152341 (Fodinicurvata sediminis); CAD42450 (Pseudomonas putida); SDW10134 (Pseudomonas kuykendallii); AAQ82900 (Pseudomonas stutzeri); ZP_00765639 (Chloroflexus aurantiacus J-10-fl); 2CY8 (Pseudomonas Strutzeri St-201);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

2CY8

Domain interval

42-365

Catalytic site

269 K

References

Walton CJ, Thiebaut F, Brunzelle JS, Couture JF, Chica RA (2018) Structural determinants of the stereo-inverting activity of Pseudomonas stutzeri D-phenylglycine aminotransferase Biochemistry 57 5437-5446.

Chantarasiri A, Meevootisom V, Isarangkul D, Wiyakrutta S. (2012) Effective improvement of D-phenylglycine aminotransferase solubility by protein crystal contact engineering J Mol Microbiol Biotechnol 22 147-55.

Müller U, van Assema F, Gunsior M, Orf S, Kremer S, Schipper D, Wagemans A, Townsend CA, Sonke T, Bovenberg R, Wubbolts M. (2006) Metabolic engineering of the E. coli L-phenylalanine pathway for the production of D-phenylglycine (D-Phg) Metab Eng 8 196-208.

Wiyakrutta S, Meevootisom V. (1997) A stereo-inverting D-phenylglycine aminotransferase from Pseudomonas stutzeri ST-201: purification, characterization and application for D-phenylglycine synthesis J Biotechnol 55 193-203.

Articles on 2.6.1.72

last changed

2017/07/24 14:07