|
|
| |
2.6.1.79 |
| Activity |
2.6.1.79 |
| Description |
Glutamate--prephenate aminotransferase |
| Notes |
The family includes plant enzymes, but strictly related to bacterial aspartate aminotransferases (family 2.6.1.1_b) and phosphonoalanine aminotransferases. |
| PDB |
5WMH; |
| PLP Fold Type |
I |
| PLP-dependent Domain |
|
| Number of sequences |
9 |
| Sequences in seed alignment |
|
| Reference sequence |
NP_565529 |
| Domain interval |
99-462 |
| Catalytic site |
306 K |
| | |
|---|
| References |
Giustini C, Graindorge M, Cobessi D, Crouzy S, Robin A, Curien G, Matringe M (2019) Tyrosine metabolism: identification of a key residue in the acquisition of prephenate aminotransferase activity by 1β aspartate aminotransferase FEBS J 286 2118-2134. Holland CK, Berkovich DA, Kohn ML, Maeda H, Jez JM (2018) Structural basis for substrate recognition and inhibition of prephenate aminotransferase from Arabidopsis Plant J 94 304-314. Graindorge M, Giustini C, Jacomin AC, Kraut A, Curien G, Matringe M. (2010) Identification of a plant gene encoding glutamate/aspartate-prephenate aminotransferase: The last homeless enzyme of aromatic amino acids biosynthesis FEBS Lett 584 4357-60. Maeda H, Yoo H, Dudareva N. (2010) Prephenate aminotransferase directs plant phenylalanine biosynthesis via arogenate Nat Chem Biol 7 19-21. |
| last changed |
2019/02/25 09:57 |
|
Browse:
Analyse:
Find: