B6db families : 2_6_1

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2.6.1.81

Activity

2.6.1.81

Description

Succinylornithine transaminase

Notes

The family was built based on two validated genes (from P. aeruginosa and E. coli). The sequences within this bacterial family are very similar to EC 2.6.1.11 (Acetylornithine aminotransferase)

PDB

4ADE;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

ASTC_ECOLI (Escherichia coli K12); YP_001334884 (Klebsiella pneumoniae); ZP_00830707 (Yersinia frederiksenii ATCC 33641); KES24870 (Pseudomonas sp. AAC); ARUC_PSEAE (Pseudomonas aeruginosa); YP_001479073 (Serratia proteamaculans 568); YP_609377 (Pseudomonas entomophila L48);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

ARUC_PSEAE

Domain interval

27-348

Catalytic site

255 K

References

Newman J, Seabrook S, Surjadi R, Williams CC, Lucent D, Wilding M, Scott C, Peat TS. (2013) Determination of the structure of the catabolic N-succinylornithine transaminase (AstC) from Escherichia coli PLoS One. 8 e58298.

Schneider BL, Kiupakis AK, Reitzer LJ. (1998) Arginine catabolism and the arginine succinyltransferase pathway in Escherichia coli J Bacteriol 180 4278-86.

Itoh Y. (1997) Cloning and characterization of the aru genes encoding enzymes of the catabolic arginine succinyltransferase pathway in Pseudomonas aeruginosa J Bacteriol 179 7280-90.

Articles on 2.6.1.81

last changed

2014/03/18 13:41