B6db families : 2_6_1

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2.6.1.93

Activity

2.6.1.93

Description

Neamine transaminase

PDB

6CBK;6CBN;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

Q53U08 (Streptomyces fradiae); Q4H4F5 (Bacillus circulans); WP_078654348 (Streptomyces catenulae); CAF32385 (Streptomyces rimosus subsp. paromomycinus); CAG34709 (Streptomyces ribosidificus); CAG38707 (Streptomyces lividus);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

Q53U08

Domain interval

42-368

Catalytic site

231 K

References

Dow GT, Thoden JB, Holden HM (2018) The Three-Dimensional Structure of NeoB: An Aminotransferase Involved in the Biosynthesis of Neomycin Protein Sci 27 945-956.

Clausnitzer D, Piepersberg W, Wehmeier UF. (2011) The oxidoreductases LivQ and NeoQ are responsible for the different 6'-modifications in the aminoglycosides lividomycin and neomycin J Appl Microbiol 111 642-51.

Huang F, Spiteller D, Koorbanally NA, Li Y, Llewellyn NM, Spencer JB. (2007) Elaboration of neosamine rings in the biosynthesis of neomycin and butirosin. Chembiochem 8 283-8.

Articles on 2.6.1.93

last changed

2018/03/19 09:01