B6db families : 2_8_1_7

	Activities \| Families \| Sequences \| Fold types \| References \| Help

2.8.1.7 a

Activity

2.8.1.7

Description

Cysteine desulfurase (family a)

Notes

This family encompasses eukariotic (mitochondrial) and bacterial cysteine desulfurases belonging to the ISC and SUF systems (these systems, devoted to the biosynthesis of iron-sulfur centers also include scaffold proteins, which function as sulfur and iron acceptors, as well as a variable number and type of accessory components).
Homologs of these proteins occur in archaea, but they have not been included here because none of them has been functionally validated.

Proteins in this family are phylogenetically related to selenocysteine lyases (EC 4.4.1.16), and often show some selenocysteine lyase activity.

PDB

1ECX;1P3W;6M4J;

PLP Fold Type

I

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

70

Sequences in seed alignment

B6db sequences :

Access denied

Users from group guest are not allowed to request page Xsearch .
To be granted access to that page you can select one of the following options:
login with your username here
... or you can give up and ...

These pages are best viewed with any standards compliant browser (e.g. Mozilla).

Reference sequence

ISCS_ECOLI

Domain interval

5-369

Catalytic site

206 K

References

B6db references :

Access denied

Users from group guest are not allowed to request page Xsearch .
To be granted access to that page you can select one of the following options:
login with your username here
... or you can give up and ...

These pages are best viewed with any standards compliant browser (e.g. Mozilla).

Articles on 2.8.1.7.a

last changed

2020/05/08 01:57