B6db families : 4_1_1_105

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4.1.1.105 b

Activity

4.1.1.105

Description

L-tryptophan decarboxylase (family b)

Notes

Family of bacterial enzymes, based on the validated sequence from Clostridium sporogenes and most closely related to family 4.1.25b (archaeal tyrosine decarboxylases).

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

WP_090038454 (Clostridium frigidicarnis); WP_010292104 (Clostridium senegalense); EDU35915 (Clostridium sporogenes ATCC 15579);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

EDU35915

Domain interval

83-360

Catalytic site

263 K

References

Williams BB, Van Benschoten AH, Cimermancic P, Donia MS, Zimmermann M, Taketani M, Ishihara A, Kashyap PC, Fraser JS, Fischbach MA (2014) Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine Cell Host Microbe 16 495-503.

Articles on 4.1.1.105.b

last changed

2018/05/18 18:13