B6db families : 4_1_1

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4.1.1.116

Activity

4.1.1.116

Description

D-ornithine/D-lysine decarboxylase

Notes

Bacterial enzymes, similar to diaminopymelate decarboxylases (Family 4.1.1.20). The family is based on the single validated sequence from Salmonella.

PDB

6N2H;

PLP Fold Type

III

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type III

Number of sequences

Sequences in seed alignment

Bacteria

AAL21261 (Salmonella enterica subsp. enterica serovar Typhimurium str. LT2); WP_016473728 (Sutterella wadsworthensis); WP_075652048 (Vibrio ponticus); WP_065798940 (Gilliamella apicola); WP_039184688 (Hafnia paralvei); WP_045043036 (Photobacterium kishitanii); WP_003364851 (Clostridium botulinum); AGH75084 (Edwardsiella piscicida); WP_048600234 (Rubeoparvulum massiliense); WP_042281057 (Clostridium sp. CL-2); KEH90675 (Clostridium novyi A str. BKT29909);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

AAL21261

Domain interval

48-420

Catalytic site

80 K

References

Phillips RS, Poteh P, Krajcovic D, Miller KA, Hoover TR (2019) Crystal Structure of d-Ornithine/d-Lysine Decarboxylase, a Stereoinverting Decarboxylase: Implications for Substrate Specificity and Stereospecificity of Fold III Decarboxylases Biochemistry 58 1038-1042.

Phillips RS, Poteh P, Miller KA, Hoover TR (2017) STM2360 encodes a d-ornithine/d-lysine decarboxylase in Salmonella enterica serovar typhimurium Arch Biochem Biophys 634 83-87.

Articles on 4.1.1.116

last changed

2019/03/25 10:27