B6db families : 4_1_1_18

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4.1.1.18 a

Activity

4.1.1.18

Description

Lysine decarboxylase (family a)

Notes

Family built around three functionally validated enzymes from leguminosae.
These are Fold-type III sequences, very closely related to those in family 4.1.17_1 (ornithine decarboxylases).

PLP Fold Type

III

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type III

Number of sequences

Sequences in seed alignment

Viridiplantae

BAK32801 (Echinosophora koreensis); ESW08124 (Phaseolus vulgaris); NP_001236340 (Glycine max); ESW08125 (Phaseolus vulgaris); XP_016165417 (Arachis ipaensis); XP_020218427 (Cajanus cajan); BAK32797 (Lupinus angustifolius); XP_003603845 (Medicago truncatula); XP_004500902 (Cicer arietinum); BAK32800 (Sophora flavescens);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

BAK32800

Domain interval

66-422

Catalytic site

91 K

References

Bunsupa S, Katayama K, Ikeura E, Oikawa A, Toyooka K, Saito K, Yamazaki M. (2012) Lysine decarboxylase catalyzes the first step of quinolizidine alkaloid biosynthesis and coevolved with alkaloid production in leguminosae. Plant Cell. 24 1202-16.

Articles on 4.1.1.18.a

last changed

2018/05/03 15:58