B6db families : 4_1_1

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4.1.1.53

Activity

4.1.1.53

Description

Phenylalanine decarboxylase

Notes

Family of fungal enzymes, strictly related to bacterial tyrosine decarboxylases (family 4.1.1.25 a).

PDB

6EBN;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Fungi

KDQ13342 (Botryobasidium botryosum FD-172 SS1); PPQ94835 (Psilocybe cyanescens); MH710581 (Psilocybe cubensis); KJA22450 (Hypholoma sublateritium FD-334 SS-4); OCB90769 (Sanghuangporus baumii);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

MH710581

Domain interval

69-530

Catalytic site

443 K

References

Torrens-Spence MP, Liu CT, Pluskal T, Chung YK, Weng JK (2018) Monoamine biosynthesis via a noncanonical calcium-activatable aromatic amino acid decarboxylase in psilocybin mushroom ACS Chem Biol 13 3343–3353.

Articles on 4.1.1.53

last changed

2018/12/19 09:54