B6db families : 4_1_1

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4.1.1.64

Activity

Description

2,2-dialkylglycine decarboxylase (pyruvate)

Notes

Compact family, composed solely of bacterial and fungal enzymes. The activity is not documented in other organisms.

PDB

PLP Fold Type

PLP-dependent Domain

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria	NP_631581 (Streptomyces coelicolor); ZP_00030273 (Burkholderia fungorum); DGDA_BURCE (Burkholderia cepacia); NP_396235 (Agrobacterium tumefaciens); ZP_00064168 (Leuconostoc mesenteroides); AAL17943 (Mycobacterium smegmatis);
Fungi	XP_328329 (Neurospora crassa); EAA74692 (Gibberella zeae); NP_594998 (Schizosaccharomyces pombe); AAM18795 (Mycosphaerella graminicola); EAA52810 (Magnaporthe grisea); EAA61842 (Aspergillus nidulans);

Reference sequence

DGDA_BURCE

Domain interval

28-367

Catalytic site

272 K

References

Adachi, K.; Nelson, G.H.; Peoples, K.A.; DeZwaan, T.M.; Skalchunes, A.R.; Heiniger, R.W.; Shuster, J.R.; Hamer, L.; Tanzer, M.M. (2003) Sequence analysis and functional characterization of the dialkylglycine decarboxylase gene DGD1 from Mycosphaerella graminicola Curr genet 43 358-63.

Keller, J. W.; Baurick, K. B.; Rutt, G. C.; O'Malley, M. V.; Sonafrank, N. L.; Reynolds, R. A.; Ebbesson, L. O.; Vajdos, F. F. (1990) Pseudomonas cepacia 2,2-dialkylglycine decarboxylase. Sequence and expression in Escherichia coli of structural and repressor genes J Biol Chem 265 5531-9.

Articles on 4.1.1.64

last changed

2008/01/30 13:54