B6db families : 4_2_3

	Activities \| Families \| Sequences \| Fold types \| References \| Help

4.2.3.2

Activity

4.2.3.2

Description

Ethanolamine-phosphate phospho-lyase

PDB

5G4J;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

WP_004681048 (Brucella melitensis); WP_012271458 (Pseudomonas putida); WP_046040370 (Pseudomonas fluorescens); WP_011777170 (Paenarthrobacter aurescens); KMO81976 (Mycobacterium obuense);

Metazoa

XP_005927740 (Haplochromis burtoni); XP_005515278 (Columba livia); NP_001086637 (Xenopus laevis); XP_001503593 (Equus caballus); XP_002717204 (Oryctolagus cuniculus); XP_006274550 (Alligator mississippiensis); XP_001364959 (Monodelphis domestica); XP_005019894 (Anas platyrhynchos); XP_006629808 (Lepisosteus oculatus); XP_005288000 (Chrysemys picta bellii); XP_003749444 (Rattus norvegicus); NP_112569 (Homo sapiens);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

NP_112569

Domain interval

25-433

Catalytic site

278 K

References

Cuetos A, Steffen-Munsberg F, Mangas Sanchez J, Frese A, Bornscheuer UT, Höhne M, Grogan G (2016) Structural Basis for Phospholyase Activity of a Class III Transaminase Homologue Chembiochem 17 2308-2311.

Veiga-da-Cunha, M., Hadi, F., Balligand, T., Stroobant, V. and Van Schaftingen, E. (2012) Molecular identification of hydroxylysine kinase and of ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and phosphoethanolamine. J. Biol. Chem. 287 7246-7255.

Articles on 4.2.3.2

last changed

2019/02/13 13:29