B6db families : 4_4_1_35

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4.4.1.35 a

Activity

4.4.1.35

Description

L-cystine β-lyase (family a)

Notes

Cyanobacterial family, buit around the well-characterized enzyme from Synechocystis.
The family shows a distant homology to family 4.4.1.16_a (selenocysteine lyase). The sequences are apparently unrelated to those of plant cystine lyases (family b).

PDB

1N2T;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

AAD02935 (Synechocystis sp. PCC 6714); ZP_00073524 (Trichodesmium erythraeum IMS101); BAC91891 (Gloeobacter violaceus); NP_683117 (Thermosynechococcus elongatus BP-1); NP_487250 (Nostoc sp. PCC 7120); ZP_00112725 (Prochlorococcus marinus str. MIT 9313); ZP_00115905 (Synechococcus sp. );

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

AAD02935

Domain interval

21-348

Catalytic site

223 K

References

Lang, T.; Kessler, D. (1999) Evidence for cysteine persulfide as reaction product of L-Cyst(e)ine C-S-lyase (C-DES) from Synechocystis. Analyses using cystine analogues and recombinant C-DES J Biol Chem 274 189-95.

Articles on 4.4.1.35.a

last changed

2018/07/18 09:33